Direct and indirect evidence suggests that the prelimbic cortex (PrL) and the ventral tegmental area (VTA) are the key brain regions involved in the regulation of itch sensation and itch-related emotions. The PrL projects widely to various cortical and subcortical brain regions. with the VTA being one of the main targets of PrL descending projections. However. https://thebrickes.shop/product-category/fabric-spray/